See single molecules in their native state. No labels required.

Refeyn revolutionizes biomolecular analysis. Measure the mass of single molecules label-free, in their native state, and get critical insights into purity, interactions, and heterogeneity – faster than ever before.

As of May 26th, our consumables pricing has changed, and our catalog has been adjusted to better meet your needs. These updates are based on the valuable feedback you provided in our survey earlier this year.
Thank you for helping us improve!

How mass photometry works

Our technology uses light scattering to measure the mass of individual molecules and viral capsids with accuracy and precision. Here’s a simplified look at the process.

What can you do with mass photometry?

Our technology is transforming research in a wide range of fields.

AAVs

Precisely characterize AAV preparations by accurately determining empty versus full capsid ratios, aggregation states, and overall integrity. Crucial for optimizing production and ensuring the safety and efficacy of gene therapies.

AdVs

Gain direct, label-free insights into AdV quality by assessing particle concentration, aggregation, and purity. This enables better control over manufacturing processes for gene delivery vectors and oncolytic agents.

Antibody aggregation

Accurately detect and quantify antibody aggregates in solution – faster and with far less sample than SEC and AUC. Essential for optimizing formulation conditions, improving stability, and ensuring safe, effective biotherapeutics.

Antibody characterization

Comprehensively profile bispecific and multi-specific antibody-antigen interactions, including stoichiometry. Ideal for new modalities, complements SPR and BLI, aiding experimental design and the interpretation of data on multi-component systems.

Membrane protein analytics

Analyze membrane proteins in native-like environments, determining oligomeric states, complex formation, and sample purity. Critical for advancing structural studies, functional assays, and therapeutic development.

mRNA

Characterize mRNA integrity and its formulation in lipid nanoparticles (LNPs). Assess size distribution, encapsulation efficiency, and stability of mRNA-LNP complexes, vital for developing and quality controlling mRNA-based vaccines and therapies.

Protein interactions

Directly measure complex formation, stoichiometry, and binding strength to reveal how proteins interact in solution. Vital for understanding biological mechanisms, validating targets, and accelerating drug discovery.

Explore our mass photometry resources

Handbook
Cover of Handbook Mass Photometry

Understanding mass photometry handbook

Curious how mass photometry delivers accurate results – fast? Whether you’re new to the technique or looking to get more from your experiments, our handbook Understanding Mass Photometry is your essential guide.

Webinar

Mass photometry 101 webinar

Curious why mass photometry has been highlighted in over 1,000 scientific publications from leading institutions like GSK, Pfizer, AstraZeneca, Bristol Myers Squibb, Harvard, Columbia, and NIH? Here’s your chance to find out.

Brochure
New Brochure

Bioanalytics with mass photometry

Explore Refeyn’s brochure to discover how mass photometry transforms discovery and drug development with rapid, label-free insights into purity, interactions, and vector quality.

The Refeyn advantage

Clarity. Speed. Simplicity.

At the heart of Refeyn’s innovation lies a commitment to providing truly insightful biomolecular data without the traditional trade-offs. Our mass photometry platform is engineered to deliver clear, actionable results quickly and simply, fundamentally changing how you approach characterization.

Peer-reviewed publications
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Global installations since Refeyn was founded
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Originating from the University of Oxford

Read our story ➞

ABL Europe

We’re generating data to compare mass photometry with gold standards like AUC and cryoTEM. Early indications show that it’s much quicker and equally accurate. Partners who’ve compared mass photometry to other methods themselves vouch for its accuracy. It’s a game changer in AAV characterization, for us as well as our clients.

Quentin Bazot

Process Development and Innovation Manager

Browse Testimonials ➞

Refeyn’s mass photometry solutions

We offer a range of mass photometers to suit different applications and budgets. Find the perfect instrument for your lab.

TwoMP product family

Measure the molecular mass of mRNA, antibodies and other proteins with speed, accuracy, and simplicity. Automated version available.

SamuxMP product family

Rapidly quantify empty, partially filled and full AAV capsids for development and manufacturing. Automated version available.

KaritroMP product family

Gain insights into size, purity and stability to quickly characterize samples of larger viral vectors or virus-like particles.

Our team

At Refeyn, our courageous, creative, and caring team is at the heart of our innovation. We are a diverse group of individuals united by a shared passion for accelerating discovery, basic research, drug development, and manufacturing through cutting-edge mass photometry technology. We believe in fostering a collaborative and supportive environment where every team member can thrive and contribute to our mission of challenging the status quo in bioanalytical techniques.

We are constantly growing and looking for talented individuals to join our team. If you are passionate about making a real impact in the world of scientific research and development, we encourage you to explore career opportunities with us.

Ready to revolutionize your research?

Find out how mass photometry can transform your sample characterization. Whether you’re focused on drug development, discovery science, or manufacturing, Refeyn’s innovative technology provides the insights you need to accelerate your breakthroughs.