
Featured Publications
Check out all the newest publications, reviews, and articles featuring mass photometry. Use the filters to find specific application areas, biomolecule types, and more.
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February 2023
Pore-Forming Proteins: From Pore Assembly to Structure by Quantitative Single-Molecule Imaging
International Journal of Molecular Sciences (2023)
Margheritis, E., Kappelhoff, S., Cosentino, K.
Keywords:
pore-forming proteins, protein complex stoichiometry, single-molecule fluorescence microscopy, super-resolution microscopy, pore functionality
February 2023
The structural mechanism of MCIA complex assembly links mitochondrial redox pathways
BioRxiv (2023)
McGregor, L., Acajjaoui, S., Desfosses, A., Saidi, M., Bacia-Verloop, M., Schwarz, J.J., Juyoux, P., von Velsen, J., Bowler, M.W., McCarthy, A., Kandiah, E., Leonard, G., Gutsche, I., Soler-Lopez, M.
Keywords:
Oxidative phosphorylation (OXPHOS), Fatty Acid Oxidation (FAO), Mitochondrial Complex I
Assembly Complex (MCIA), Cryo-EM, Amyloid-β, ECSIT phosphorylation
February 2023
Biophysical Dissection of Isolated GPCRs: The Adenosine A2A Receptor under the Bistouries
Receptors (2023)
Banères, J.-L., Botzanowski, T., Boutin, J.A., Calamini, B., Castel, J., Catoire, L.J., Cianférani, S., Demesmay, C., Ferguson, G., Ferry, G., Kniazeff, J., Krimm, I., Langer, T., Lebon, G., Ley, M., Nyerges, M., Schwob, M., Venien-Bryan, C., Wagner, R., Zeder-Lutz, G., Zilian-Stohrer, C.
Keywords:
adenosine receptor A2A, biophysical approach, NMR, mass spectrometry, molecular pharmacology, expression, purification, reconstitution, ligands, techniques, review
November 2022
Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses
BioRxiv (2023)
Radić, L., Sliepen, K., Yin, V., Brinkkemper, M., Capella-Pujol, J., Schriek, A.I., Torres, J.L., Bangaru, S., Burger, J.A., Poniman, M. Bontjer, I., Bouhuijs, J.H., Gideonse, D., Eggink, D., Ward, A.B., Heck, A.J.R., Van Gils, M.J., Sanders, R.W., Schinkel, J.
Keywords:
bispecific antibodies; antibody neutralization; mass photometry; SARS-CoV-2; VOC;
53 sarbecoviruses; avidity; controlled Fab-arm exchange
February 2023
C-terminus induced asymmetry within a Rad52 homodecamer dictates single-position Rad51 nucleation in homologous recombination
BioRxiv (2023)
Deveryshetty, J., Chadda, R., Mattice, J., Karunakaran, S., Rau, M.J., Basore, K., Pokhrel, N., Englander, N., Fitzpatrick, J.A.J., Bothner, B., Antony, E.
Keywords:
Homologous recombination, cryoEM, protein-nucleotide interactions, Rad51, Rad52, ssDNA