Featured publications


McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation

Hajdusits B., Suskiewicz M.J., Hundt N., et al. 

bioRxiv 2020.09.08.287243; doi: https://doi.org/10.1101/2020.09.08.287243


Equilibrium Binding Model for CpG DNA-Dependent Dimerization of Toll-like Receptor 9 Ectodomain

Reikine S., McLaughlin S.H., and Modis Y.

Biochemistry Article ASAP
DOI: 10.1021/acs.biochem.0c00466


Rapid high-yield expression and purification of fully post-translationally modified recombinant clusterin and mutants

Satapathy, S., Dabbs, R.A. & Wilson, M.R.

Sci Rep 10, 14243 (2020). https://doi.org/10.1038/s41598-020-70990-3

JULY 2020

Structures of fungal and plant acetohydroxyacid synthases

Lonhienne, T., Low, Y.S., Garcia, M.D. et al.

Nature (2020). https://doi.org/10.1038/s41586-020-2514-3

JULY 2020

Quantifying the monomer-dimer equilibrium of tubulin with mass photometry

APRIL 2020

Structural basis of host protein hijacking in human T-cell leukemia virus integration

Bhatt, V., Shi, K., Salamango, D.J. et al. 

Nat Commun 11, 3121 (2020). https://doi.org/10.1038/s41467-020-16963-6

APRIL 2020

Characterization of CaMKIIα Holoenzyme Stability

APRIL 2020

Quantifying the heterogeneity of macromolecular machines by mass photometry

Sonn-Segev A, Belacic K, Bodrug T, et al. 

Nat Commun 11, 1772 (2020). https://doi.org/10.1038/s41467-020-15642-w


Single-molecule fluorescence-based approach reveals novel mechanistic insights into small heat shock protein chaperone function


Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas

JUNE 2019

Dissecting FOXP2 Oligomerization and DNA Binding

APRIL 2018

Quantitative mass imaging of single biological macromolecules


Headless C1q: a new molecular tool to decipher its collagen‐like functions

Fouët G., Bally I., Signor L., et al.


FEBS Journal (August 2020), https://doi.org/10.1111/febs.1554


Emergence and Rearrangement of Dynamic Supramolecular Aggregates Visualized by Interferometric Scattering Microscopy

Lebedeva M.A., Palmieri E., Kukura P. et al.

ACS Nano Article ASAP. DOI: 10.1021/acsnano.0c02414


Single molecule mass photometry of nucleic acids

Yiwen Li, Weston B. Struwe, Philipp Kukura

Nucleic Acids Research, gkaa632, https://doi.org/10.1093/nar/gkaa632

JULY 2020

Synthesis and Characterization of Dendrimer-Based Polysarcosine Star Polymers: Well-Defined, Versatile Platforms Designed for Drug-Delivery Applications

England R.M., Moss J.I., Gunnarsson A., et al.

Biomacromolecules 2020 21 (8), 3332-3341
DOI: 10.1021/acs.biomac.0c00768

JUNE 2020

A wealth of genotype-specific proteoforms fine-tunes hemoglobin scavenging by haptoglobin

APRIL 2020

Myosin II Filament Dynamics in Actin Networks Revealed with Interferometric Scattering Microscopy

APRIL 2020

Quantifying protein-protein interactions by molecular counting with mass photometry

MARCH 2020

Measuring the affinity of protein-protein interactions on a single-molecule level by mass photometry


Mass Photometry of Membrane Proteins

Olerinyova A, Sonn Segev A , Gault J, et al. 

bioRxiv 2020.02.28.969287; doi: https://doi.org/10.1101/2020.02.28.969287


Membrane insertion of soluble CLIC1 into active chloride channels is triggered by specific divalent cations

Varela L, Hendry A, Medina-Carmona E, et al.

bioRxiv 638080; doi: https://doi.org/10.1101/638080

MAY 2019

 An ultra-stable gold-coordinated protein cage displaying reversible assembly

Malay A, Miyazaki N, Biela A, et al.

Nature 2019 569:438–442 


Label-Free Single-Molecule Imaging with Numerical-Aperture-Shaped Interferometric Scattering Microscopy

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