Featured publications

JUNE 2020

A wealth of genotype-specific proteoforms fine-tunes hemoglobin scavenging by haptoglobin

APRIL 2020

Quantifying protein-protein interactions by molecular counting with mass photometry

MARCH 2020

Measuring the affinity of protein-protein interactions on a single-molecule level by mass photometry

APRIL 2020

Characterization of CaMKIIα Holoenzyme Stability


Single molecule mass photometry of nucleic acids


Membrane insertion of soluble CLIC1 into active chloride channels is triggered by specific divalent cations

Varela L, Hendry A, Medina-Carmona E, et al.

bioRxiv 638080; doi: https://doi.org/10.1101/638080

MAY 2019

 An ultra-stable gold-coordinated protein cage displaying reversible assembly

Malay A, Miyazaki N, Biela A, et al.

Nature 2019 569:438–442 


Label-Free Single-Molecule Imaging with Numerical-Aperture-Shaped Interferometric Scattering Microscopy

APRIL 2020

Structural basis of host protein hijacking in human T-cell leukemia virus integration

Bhatt, V., Shi, K., Salamango, D.J. et al. 

Nat Commun 11, 3121 (2020). https://doi.org/10.1038/s41467-020-16963-6

APRIL 2020

Quantifying the heterogeneity of macromolecular machines by mass photometry

Sonn-Segev A, Belacic K, Bodrug T, et al. 

Nat Commun 11, 1772 (2020). https://doi.org/10.1038/s41467-020-15642-w


Mass Photometry of Membrane Proteins

Olerinyova A, Sonn Segev A , Gault J, et al. 

bioRxiv 2020.02.28.969287; doi: https://doi.org/10.1101/2020.02.28.969287


Single-molecule fluorescence-based approach reveals novel mechanistic insights into small heat shock protein chaperone function


Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas

JUNE 2019

Dissecting FOXP2 Oligomerization and DNA Binding

APRIL 2018

Quantitative mass imaging of single biological macromolecules

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