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Featured Publications

Check out all the newest publications, reviews, and articles featuring mass photometry. Use the filters to find specific application areas, biomolecule types, and more.

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December 2023

Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1

Nature Structural and Molecular Biology (2024)

Duering, J., Wolter, M., Toplak, J., Torres, C., Dybkov, O., Fokkens, T., Bohnsack, K., Urlaub, H., Steinchen, W., Dienemann, C., Lorenz, S.

Keywords:

E3, enzyme mechanism, RAC1, cryo-EM, SAXS, hydrogen-deuterium exchange mass spectrometry, crosslinking

May 2024

Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation

Immunity (2024)

Bérouti, M., Lammens, K., Heiss, M., Hansbauer, L., Bauernfried, S., Stöckl, J., Pinci, F., Piseddu, I., Greulich, W., Wang, M., Jung, C., Fröhlich, T., Carell, T., Hopfner, K.P., Hornung, V.

Keywords:

TLR7, RNase T2, PLD3, PLD4, plasmacytoid dendritic cell, RNA sensing

March 2024

Sequential conformational transition of ArnB, an archaeal ortholog with Sec23/Sec24 core motif

Research Square (2024)

Essen, L., Korf, L. Steinchen, W., Watad, M., Bezold, F., Vogt, M., Selbach, L., Penner, A., Tourte, M., Hepp, S., Albers, S.

Keywords:

ArnB, Sec23/24, sequential phosphorylation, order to disorder, bidirectional transition

May 2024

The complete assembly of human LAT1-4F2hc complex provides insights into its regulation, function and localisation

Nature Communications (2024)

Wu, D., Yan, R., Song, S., Swansiger, A.K., Li, Y., Prell, J.S., Zhou, Q., & Robinson, C.V.

Keywords:

Mass spectrometry, Membrane proteins, Structural biology, oligomerization, detergent

April 2024

Local environment in biomolecular condensates modulates enzymatic activity across length scales

Nature Communications (2024)

Gil-Garcia, M., Benítez-Mateos, A.I., Papp, M., Stoffel, F., Morelli, C., Normak, K., Makasewicz, K., Faltova, L., Paradisi, F., & Arosio, P.

Keywords:

Biophysical chemistry, Intrinsically disordered proteins, Protein design

April 2024

Resolving multiple conformations of a sub-80 kDa Chagas vaccine candidate by cryo-EM led integrative approach

Research Square (2024)

Campeotto, I., Batra, S., Ragan, T., Frank, A., Kaplan, M., Lancey, C., Assadipapari, M., Ying, C., Struwe, W., Hesketh, E., Barfod, L.

Keywords:

Chagas disease, cryo-EM, enzymology, SAX, MD, plasmonic optical tweezers, antibodies, protein interaction

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