Mass photometry of nanocages

Application Note

Ferritins naturally form nanocages to store and transport iron and are of interest in the fields of nanomedicine and drug delivery. The interior cavity of ferritins can be loaded with a variety of small molecules upon pH-induced disassembly and reassembly and the outer surface functionalised for targeting or soliciting a host response.


Here, we show how mass photometry can be used to quantify assembly, load and homogeneity at single particle resolution. Such measurements use little sample, are fast, label-free, and broadly applicable to natural and synthentic nanocages.

Download the application note

Fill in your details to receive the application note via e-mail. In case you do not receive it, please check your spam or junk folder, or contact us.

By clicking submit you will be subscribed to our mailing list and will receive occasional updates from Refeyn. Your address and personal information will be stored securely. We will not sell or share this information with anyone.


More Application Notes

Browse through our catalogue of application notes highlighting some recent case studies featuring mass photometry.

Mass photometry of nucleic acids

Mass photometry on SARS-CoV-2

Mass photometry of AAVs

Basics of Mass Photometry

Stay connected!

Join our mailing list to receive regular updates from Refeyn.

Contact Us

Refeyn Ltd.

1 Electric Avenue, Ferry Hinksey Road,

Oxford OX20BY

  • YouTube
  • LinkedIn
  • Twitter

Useful Links