Applications of mass photometry

Mass photometry is a completely new addition to the bioanalytical tool kit. By directly measuring molecular mass in solution, it reports on fundamental properties of the sample while maintaining the native environment. It is thus widely applicable to a range of different molecules and steps in both basic research and in drug discovery processes. 

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Mass photometry measures mass at the single molecule level, providing insights into the composition and function of even complex samples and molecular mechanisms. This unique technology can be used to detect and characterise proteins, nucleic acids, lipids and / or sugars, providing information on structure (oligomeric state, modification), homogeneity, and function (quantifying interactions) – all in a matter of minutes, and using tiny amounts of sample.

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Due to its unique benefits, mass photometry addresses  a major unmet need for more efficient analytical tools, and will ultimately help accelerate science and the discovery and development of new therapeutics.