Quantifying the heterogeneity of macromolecular machines by mass photometry
A recent preprint in BioRxiv showcases mass photometry's potential as a tool to analyse evaluate the composition of complex protein samples in an efficient manner.
Like the authors, we also believe that mass photometry's ability to analyse multiple properties, such as homogeneity, structural integrity and activity in complex mixtures is going to be a very useful tool for structural biologists. Our congratulations to the authors!
Read the full preprint here -
Quantifying the heterogeneity of macromolecular machines by mass photometry Adar Sonn-Segev, Katarina Belacic, Tatyana Bodrug, Gavin Young, Ryan T. VanderLinden, Brenda A. Schulman, Johannes Schimpf, Thorsten Friedrich, Phat Vinh Dip, Thomas U. Schwartz, Benedikt Bauer, Jan-Michael Peters, Weston B. Struwe, Justin L. P. Benesch, Nicholas G. Brown, David Haselbach, Philipp Kukura
bioRxiv 864553; doi: https://doi.org/10.1101/864553