Mass Photometry with detergents
Application Note

Detergents are widely used in biochemistry but display complex behaviour in aqueous solutions. Mass photometry is an effective tool for the study of biomolecules in detergent-containing solutions as well as for the evolution of molecular aggregation and micelle formation. Here, we describe how detergents affect mass photometry measurements and outline recommendations for how to optimise conditions for mass photometry experiments involving detergents.